SS-31 (Elamipretide)
Overview
SS-31, also known as Elamipretide, is a synthetic tetrapeptide that targets mitochondria to reduce oxidative stress and improve energy production. It offers a promising approach for researchers studying mitochondrial dysfunction, cardiovascular health, and neurodegenerative diseases, with potential applications in aging and metabolic studies. Its mitochondrial protective effects make it a valuable tool for cellular research.
Detailed Benefits Analysis
The benefits of SS-31 can be categorized based on preclinical and clinical data, presented here for educational and research purposes:
Mitochondrial Function
- SS-31: Stabilizes cardiolipin in mitochondrial membranes, enhancing ATP production and reducing ROS. Studies in heart failure models showed improved mitochondrial function, making it a candidate for mitochondrial disorder research.
Cardiovascular Health
- SS-31: Protects against ischemia-reperfusion injury by reducing oxidative damage. Clinical trials in heart failure patients showed improved cardiac function, relevant for cardiovascular research.
Neuroprotection
- SS-31: Mitigates neuronal damage by reducing mitochondrial oxidative stress. Preclinical studies in Alzheimer’s models suggest it protects neurons, beneficial for neurodegenerative research.
Anti-Aging Effects
- SS-31: May slow cellular aging by improving mitochondrial efficiency. Animal studies indicate it extends healthspan, making it a candidate for aging research.
Important Note
This product is for research purposes only and should not be used for human consumption. It’s not intended to diagnose, treat, or prevent any disease, and always follow local laws when handling research chemicals.
Structure
- Sequence: D-Arg-Dmt-Lys-Phe-NH2 (Dmt = 2',6'-dimethyltyrosine)
- Molecular Formula: C32H49N9O5
- Molecular Weight: 639.79 g/mol
- PubChem CID: 11704231
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