1 1

SLU-PP-322 (5mg)

SLU-PP-322 (5mg)

$89.00 USD
$89.00 USD

SLU-PP-322 Product Description

Overview

SLU-PP-322 is a synthetic small molecule engineered to function as a potent, non-selective agonist of the estrogen-related receptors (ERRs), with a notable affinity for ERRα. Designed for cutting-edge research in metabolic health and exercise mimetics, SLU-PP-322 activates ERR pathways without eliciting estrogenic effects, positioning it as an invaluable asset for studying cellular energy regulation, mitochondrial performance, and metabolic adaptations. By replicating the physiological benefits of endurance exercise, SLU-PP-322 provides researchers with a powerful tool to investigate its potential in addressing metabolic disorders, enhancing muscle function, and bolstering cellular resilience.

Detailed Benefits Analysis

The potential benefits of SLU-PP-322 are outlined below, categorized based on preclinical research and presented for educational and investigative purposes:

Metabolic Health

  • Energy Expenditure and Fat Oxidation: SLU-PP-322 promotes increased energy expenditure and enhances fatty acid oxidation, resulting in reduced fat mass accumulation. Studies in animal models demonstrate its ability to decrease adiposity and improve insulin sensitivity, offering a promising avenue for exploring treatments for obesity and metabolic syndrome.
  • Insulin Sensitivity: Through ERR pathway activation, SLU-PP-322 enhances glucose metabolism and insulin responsiveness, providing valuable insights into potential therapies for type 2 diabetes and related metabolic conditions.

Exercise Mimetics

  • Endurance and Muscle Function: SLU-PP-322 emulates the metabolic shifts induced by endurance training, boosting mitochondrial density and oxidative capacity in skeletal muscle. Preclinical data indicate improved exercise endurance and a shift in muscle fiber composition toward oxidative phenotypes.
  • Mitochondrial Biogenesis: This compound upregulates genes tied to mitochondrial biogenesis, such as TFAM, and enhances oxidative phosphorylation, effectively simulating the cellular effects of aerobic exercise.

Cellular Function

  • Mitochondrial Respiration: SLU-PP-322 enhances mitochondrial function and cellular respiration in skeletal muscle cell lines, improving energy production efficiency and mitigating oxidative stress.
  • Anti-Inflammatory Effects: By modulating inflammatory pathways, SLU-PP-322 exhibits potential in reducing age-related inflammation, a key factor in maintaining cellular health and longevity.

Important Note

This product is intended exclusively for research purposes and is not suitable for human consumption. It is not designed to diagnose, treat, or prevent any disease. Always adhere to local regulations when handling research chemicals.

Structure

  • SLU-PP-322
    • Chemical Formula: C₁₆H₁₄N₂O₂ (based on structural analogs; verify with specific data if available)
    • Molecular Weight: 290.32 g/mol
    • CAS Number: 303760-60-3
    • SLU-PP-322 features a hydrazone linkage connecting a 4-hydroxybenzamide moiety to a naphthalene ring system, with a Z-configuration at the C=N double bond, critical for its binding affinity to ERRs.